Virtual reality exercise (VR) has been used in combination with home-based exercise cardiac rehabilitation (CR) as an alternative for CR in cardiac outpatients. However, the safety features, the specified exercise program, and the results have certain limitations. Therefore, this workshop aims to showcase the development of a virtual reality exercise program for improving cardiovascular endurance, pulmonary function, respiratory muscle strength, and quality of life in patients with cardiovascular disease and patients with open heart surgery phase II.